Project Overview

SMART CAMP (Critical Analytics for Manufacturing Personalized-Medicine) is an interdisciplinary research programme in Singapore (CREATE international research campus and innovation hub) and at the Massachusetts Institute of Technology (MIT). SMART CAMP addresses key technology bottlenecks in cell therapy manufacturing: (i) critical quality attributes (CQA) of safe, effective cell therapy products; and (ii) integrated process analytics to monitor and modulate those attributes. Our efforts are focused on allogeneic and autologous cell therapy products, including but not limited to cell sources including adult stem/progenitor cells and immune cells for treatment of specific cancers, tissue degeneration, and autoimmune diseases.

This interdisciplinary team comprises engineers, biologists, clinicians, manufacturing, and data analytics experts from multiple MIT academic units, and multiple Singapore-based universities, research centres of excellence, and hospitals who are experienced at translational demonstrations of technologies in safety-regulated industries such as cell therapies.

SMART, MIT’s first such research unit outside of Cambridge, MA, serves as an intellectual hub, allowing faculty, researchers and graduate students from MIT to collaborate with their academic and industrial counterparts from Singapore and the region in exciting new areas of science and technology.

Key Responsibilities

• Develop high throughput microfluidic systems for high throughput cell sorting for various diseases and/or biological studies.
• Collaborate with cross-functional CAMP teammates and the broader Singapore academic and cell manufacturing communities, including engineers, clinicians, GMP manufacturers, and industry partners.
• Prepare and publish research manuscripts based on project findings.
• Contribute to intellectual property development, including patent applications for related work.
• Maintain comprehensive documentation of protocols, experimental records, and data.

Requirements

• Ph.D. degree in the area of bioengineering, biophysics, or related engineering / science departments from a reputable university.
• Familiarity with the field of microfluidics and various cell and particle sorting procedures (inertial, electrical, and others) will be a plus, although not absolutely required.
• Proactive and motivated in design and tailoring the direction of the R&D to successful outcome
• Excellent scientific writing skills for manuscript preparation and patent applications.
• Strong organizational and documentation skills to maintain protocols and data records.
• Ability to work collaboratively in an inter-disciplinary team.

Interested applicants are invited to send in their full CV/resume, cover letter and list of three references (to include reference names and contact information). We regret that only shortlisted candidates will be notified.